Perineal use of talc and risk of ovarian cancer.
نویسندگان
چکیده
Ovarian cancer is one of the most common gynaecological neoplasms, especially in industrialised countries. The aetiology of the disease is not well understood, except that inherited mutations in the breast cancer genes BRCA-1 and BRCA-2 account for up to 10% of all cases, and child-bearing, oral contraceptive use and breast-feeding reduce the risk. Some environmental exposures, notably talc and asbestos, have been suspected as ovarian carcinogens.
منابع مشابه
Perineal talc exposure and epithelial ovarian cancer risk in the Central Valley of California.
Perineal talc use has been suggested as a possible risk factor for ovarian cancer based on its structural similarity to asbestos, a known human carcinogen. A population-based epidemiologic case-control study of epithelial ovarian cancer (EOC) was conducted in 22 counties of Central California that comprise the reporting area for 2 regional cancer registries. Telephone interviews were conducted ...
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ورودعنوان ژورنال:
- Journal of epidemiology and community health
دوره 62 4 شماره
صفحات -
تاریخ انتشار 2008